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Speil, J.C., and U. Kubitscheck. 2010. Single ovalbumin molecules exploring nucleoplasm and nucleoli of living cell nuclei. BBA – Mol. Cell Res., 1803, 396-404. (PDF)

Kubitscheck, U., R. Veith, J. Ritter, and J. P. Siebrasse. 2010. Messenger-RNA Trafficking in Living Cells. In "Single Particle Tracking and Single Molecule Energy Transfer: Applications in the Bio and Nano Sciences", eds. C. Bräuchle, J. Michaelis, D.C. Lamb, Wiley-VCH Weinheim, (Review)


Sieben, A., T. Kaminski, U. Kubitscheck and H. Häberlein. 2009. Terbutaline causes immobilization of single β-2-adreneric receptor-ligand-complexes in the plasma membrane of living A549 cells as revealed by single molecule microscopy, submitted

Ciobanasu, C., E. Harms, G. Tünnemann, M.C. Cardoso, and U. Kubitscheck. 2009. Cell-penetrating HIV1 TAT peptides float on model lipid bilayers. Biochem. 48: 4728-37. (PDF)

Siebrasse, J.-P. and U. Kubitscheck. 2009. Single Substrate and Transport Receptor Molecules at the Nuclear Pore Complex. In "Nuclear Transport", ed. R. Kehlenbach, Wiley-VCH Weinheim, (Review), see

Kubitscheck, U. 2009. Single Molecule Fluorescence Monitoring in Eukaryotic Cells: Intranuclear Dynamics of Splicing Factors. In "Single Cell Analysis: Technologies and Applications", ed. D. Anselmetti, Wiley VCH (Review)

Siebrasse, J.-P., and U. Kubitscheck. 2009. Single Molecule Tracking for Studying Nucleocytoplasmic Transport and Intranuclear Dynamics. Meth. Mol. Biol. 464: 343-61. (Review)


Siebrasse, J.-P., R. Veith, A. Dobay, H. Leonhardt, B. Daneholt and U. Kubitscheck. 2008. Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin, Proc Natl Acad Sci USA 105:20291-6. Please note discussion of this paper in the "Faculty of 1000 Biology Reports 2009 1:29 (29 April 2009)"

Dange, T., G. Grünwald, A. Grünwald, R. Peters, and U. Kubitscheck. Autonomy and Robustness of Translocation through the Nuclear Pore Complex: a Single-Molecule Study, J. Cell Biol. 183, 77-86. (PDF)

Ritter, J.G., R. Veith, J.-P. Siebrasse, and U. Kubitscheck. 2008. High-contrast single-particle tracking by selective focal plane illumination microscopy. Optics Express 16: 7142-7152.

Grünwald, D, R.M. Martin, V. Buschmann, D.P. Bazett-Jones, H. Leonhardt, U. Kubitscheck, and M.C. Cardoso. 2008. Probing Intranuclear Environments at the Single Molecule Level. Biophys. J. 94, 2847-58. (PDF)

Kaminski, T., J.-P. Siebrasse, V. Gieselmann, U. Kubitscheck, and J. Kappler. 2008. Imaging and Tracking of Single Hyaluronan Molecules Diffusing in Solution. Glycoconjugate J. 25: 555-560.

Wan, Y., W. Eisinger, D. Ehrhardt, U. Kubitscheck, F. Baluska, and W. Briggs. 2008. The subcellular localization and blue-light-induced movement of phototropin 1-GFP in etiolated seedlings of Arabidopsis thaliana. Mol. Plant 1: 103-117. (PDF)


Kirchhoff, H., W. Haase, T. Schott, M. Borinski, U. Kubitscheck, M. Rögner. 2007. Structural and functional self-organization of Photosystem II in grana thylakoids, Biochim. Biophys. Acta (Bioenergetics) 1767, 1180-1188. (PDF)

Siebrasse, J.-P., D. Grünwald, and U. Kubitscheck. 2007. Single particle tracking in eukaryotic cell nuclei. Anal. Bioanal. Chem. 387:41-44. (PDF)


Grünwald, D., B. Spottke, V. Buschmann, and U. Kubitscheck. 2006. Intranuclear binding kinetics and mobility of single U1 snRNP particles in living cells; Mol. Biol. Cell, 17, 5017-5027. (PDF)

Tremmel, I., D. Grünwald, and U. Kubitscheck. Analysis of a supramolecular protein pore by single molecule fluorescence in "Center for Nanotechnology Lectures for Nanobiology", in press (Review)

Kubitscheck, U. 2006. Fluorescence Microscopy: Single Particle Tracking. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, D. Ganten and K. Ruckpaul, eds. (Review)

Grünwald, D., A. Hoekstra, T. Dange, V. Buschmann, Dr. and U. Kubitscheck. 2006. Direct Observation of Single Protein Molecules in Aqueous Solution. ChemPhysChem 7, 812-815. (PDF)


Höppener, C., J.-P. Siebrasse, R. Peters, U. Kubitscheck, and A. Naber. 2005. High-resolution near-field optical imaging of single nuclear pore complexes under physiological conditions. Biophys. J. 88: 3681-3688. (PDF)

Kubitscheck, U., D. Grünwald, A. Hoekstra, D. Rohleder, T. Kues, J.-P. Siebrasse, and R. Peters. 2005. Binding site distribution and residence time of single transport factors and import complexes in the nuclear pore. J. Cell Biol. 168: 233-243. (PDF)


Kirchhoff, H., I. Tremmel, W. Haase, and U. Kubitscheck. 2004. Supramolecular photosystem II organization in grana thylakoid membranes: Evidence for a structured arrangement. Biochem. 43 (28): 9204-9213. (PDF)


Kues, T., and U. Kubitscheck. 2002. Single molecule motion perpendicular to the focal plane of a microscope: application to splicing factor dynamics within the cell nucleus. Single Mol. 3 (4), 218-224.

Kubitscheck, U. 2002. Single protein molecules visualized and tracked in the interior of eukaryotic cells. Single Mol. 3 (5-6), 267-274 (review)

Kubitscheck, U., T. Kues, and A. Hoekstra. 2002. Visualization and tracking of single molecules within cells. GIT Imaging and Microscopy 4/2002, 41-43, und GIT Laboratory Journal, 6/2002, 293-295. (Reviews)


Kues, T., A. Dickmanns, R. Lührmann, R. Peters, and U. Kubitscheck. 2001. High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking. Proc. Natl. Acad. Sci., USA, 98(21):12021-12026.

Kues, T., R. Peters, and U. Kubitscheck. 2001. Visualization and tracking of single protein molecules in the cell nucleus. Biophys. J. 80: 2954-2967.

Schiller, M., M. Raghunath, U. Kubitscheck, T.E. Scholzen, T. Fisbeck, D. Metze, T.A. Luger, M. Böhm. 2001. Human dermal fibroblasts express prohormone convertase 1 and 2 and produce pro-opiomelanocortin-derived peptides. J. Invest. Dermatol. 117(2):227-235.

Horneffer, V., A. Forsmann, K. Strupat, F. Hillenkamp, and U. Kubitscheck. 2001. Localization of analyte molecules in MALDI preparations by confocal laser scanning microscopy. Anal. Chem. 73(5):1016-1022.

Kubitscheck, U., T. Kues, and R. Peters. 2001. Fluoreszenzmikroskopische Beobachtung einzelner Proteinmoleküle in Eukaryontenzellen. GIT Labor-Fachzeitschrift 9/2001, 922-926. (Review)


Kubitscheck, U., O. Kückmann, T. Kues, and R. Peters. 2000. Imaging and tracking of single GFP molecules in solution. Biophys. J. 78:2170-2179.

Kubitscheck, U., U. Homann, and G. Thiel. 2000. Osmotically evoked shrinking of guard cell protoplasts causes retrieval of membrane from the plasma membrane into the cytoplasm. Planta 210:423-431. 


Böhm, M., T. Brzoska, U. Schulte, M. Schiller, U. Kubitscheck, and T.A. Luger. 1999. Characterization of a polyclonal antibody raised against the human melanocortin-1 receptor. Ann. N. Y. Acad. Sci. 885:372-382.

Raghunath M., R. Cankay, U. Kubitscheck, J.-D. Fauteck, R. Mayne, D. Aeschlimann, and U. Schlötzer-Schrehardt. 1999. Transglutaminase activity in the eye: crosslinking in epithelia and connective tissue structures. Invest. Ophthalmol. Vis. Sci. 40:2780-2787.

Kubitscheck, U., T. Kues, and R. Peters. 1999. Visualization of the nuclear pore complex and its distribution by confocal laser scanning microscopy. Meth. Enzymol. 307, 207-230. (Review)

Peters, R., and U. Kubitscheck. 1999. Optical Single-Transporter Recording and Three-Dimensional Diffusion Measurements. Methods 18, 508-517. (Review)


Raghunath, M., C. Unsöld, U. Kubitscheck, L. Bruckner-Tuderman, R. Peters, and M. Meuli. 1998. The Cutaneous Microfibrillar Apparatus Contains Latent Transforming Growth Factor-? Binding Protein-1 (LTBP-1) and is a Repository for Latent TGF-?1. J. Investig. Dermatol. 111, 559-564.

Flörsheimer, M., R. Paschotta, U. Kubitscheck, Ch. Brillert, D. Hofmann, L. Heuer, G. Schreiber, C. Verbeek, W. Sohler, and H. Fuchs. 1998. Second-Harmonic Imaging of Ferroelectric Domains in LiNbO3 with Micron Resolution in Lateral and Axial Direction. Appl. Phys. B 67: 593-599.

Kubitscheck, U., P. Wedekind, and R. Peters. 1998. Three-Dimensional Diffusion Measurements by Scanning Microphotolysis: Basic Concept and Theoretical Methods. J. Microsc. 191, 126-138.

Kubitscheck, U., and R. Peters. 1998. Localization of Single Nuclear Pore Complexes by Confocal Laser Scanning Microscopy and Analysis of their Distribution. Meth. Cell Biol. 53, 79-98.


Middeler, G., K. Zerf, S. Jenovai, A. Thülig, M. Tschödrich-Rotter, U. Kubitscheck, and R. Peters. 1997. The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited. Oncogene 14, 1407-1417. (PDF)


Kubitscheck, U., O. Heinrich, and R. Peters. 1996. Continuous scanning microphotolysis employing single and two photon excitation for lateral transport measurements. Bioimaging 4, 158-167.

Wedekind, P., U. Kubitscheck, O. Heinrich and R. Peters. 1996. Line Scanning Microphotolysis for diffraction limited measurements of lateral diffusion. Biophys. J. 71, 1621-1632.

Kubitscheck U., P. Wedekind, O. Zeidler, M. Grote, and R. Peters. 1996. Single nuclear pores visualized by confocal microscopy and image processing. Biophys. J. 70, 2067-2077.

Kubitscheck U., M. Tschödrich-Rotter, P. Wedekind, and R. Peters. 1996. Two-photon scanning microphotolysis for three-dimensional data storage and biological transport measurements. J. Microsc. 182, 225-233.

Tschödrich-Rotter, M., U. Kubitscheck, G. Ugochukwu, J.T. Buckley, and R. Peters. 1996. Optical single channel analysis of the aerolysin pore in erythrocyte membranes. Biophys. J. 70, 723-732.

Peters, R. und U. Kubitscheck. 1996. Kern-Zytoplasma-Transport unter die Lupe genommen. Mitteilungen der Deutschen Gesellschaft für Zellbiologie 22 (1/96) 15-19.


Grebenkämper K., P.-F. Tosi, J.E. Zazarte, L. Sneed, U. Brüggemann, U. Kubitscheck, C. Nicolau, and R. Peters. 1995. Modulation of CD4 lateral mobility in intact cells by an intracellularly applied antibody. Biochem. J. 312, 251-259.

Grote M., U. Kubitscheck, R. Reichelt, and R. Peters. 1995. Mapping of nucleoporins to the center of the nuclear pore complex by post-embedding immunogold electron microscopy. J. Cell Sci. 108, 2963-2972.

Kubitscheck U., L. Pratsch, H. Passow, and R. Peters. 1995. Calcium pump kinetics determined in single erythrocyte ghosts by microphotolysis and confocal imaging. Biophys. J. 69, 30-41.


Wedekind P., U. Kubitscheck, and R. Peters. 1994. Scanning microphotolysis: A new photobleaching technique based on fast intensity modulation of a scanned laser beam and confocal imaging. J. Microsc. 176, 23-33.

Kubitscheck U., P. Wedekind, and R. Peters. 1994. Lateral Diffusion Measurement at High Spatial Resolution by Scanning Microphotolysis in a Confocal Microscope. Biophys. J. 67, 948-956. (PDF)


Kubitscheck U., R. Schweitzer-Stenner, D.J. Arndt-Jovin, T.M.Jovin, and I. Pecht. 1993. Distribution of type I Fc?-receptors on the surface of mast cells probed by fluorescence resonance energy transfer. Biophys. J. 64, 110-120. (PDF)


Kubitscheck U., R. Levi, R.J Horwitz, R. Arnon, and I. Pecht. 1992. Peptide binding to class I molecules of the major histocompatibility complex on the surface of living target cells. Scand. J. Immunol. 36, 341-348. (PDF)


Kubitscheck U., M. Kircheis, R. Schweitzer-Stenner, W. Dreybrodt, T.M. Jovin, and I. Pecht. 1991. Fluorescence Resonance Energy Transfer on Single Living Cells. Application to Binding of Monovalent Haptens to Cell-Bound Immunoglobulin E. Biophys. J. 60, 307-318. (PDF)


Schweitzer-Stenner R., W. Dreybrodt, D. Wedekind, and U. Kubitscheck. 1986. The Analysis of the Depolarisation Ratio Dispersion of Resonant Raman Lines in Haemproteins. A Suitable Tool to Detect Haem-Protein Interactions. J. Mol. Struct. 143, 453-456. (PDF)

Kubitscheck U., W. Dreybrodt and R. Schweitzer-Stenner. 1986. Detection of Heme-Distortions in Ferri- and Ferrocytochrome c by Resonance Raman Scattering. Spectrosc. Lett. 19(6), 681-690.

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